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What Cefuroxime is and what it is used for : · Cefuroxime is an antibiotic used in adults and children. It works by killing bacteria that cause infections. It belongs to a group of medicines called cephalosporins. Cefuroxime is used to treat infections of: the throat, sinus, middle ear, the lungs or chest, the urinary tract, the skin and soft tissues. Cefuroxime can also be used to treat Lyme disease (an infection spread by parasites called ticks). · Your doctor may test the type of bacteria causing your infection and monitor whether the bacteria are sensitive to Cefuroxime during your treatment. Do not use Cefuroxime if : · You are allergic (hypersensitive) to Cefuroxime or any of the other ingredients of Cefuroxime · You are allergic (hypersensitive) to any other cephalosporin type antibiotic · You have ever had a severe allergic reaction to any penicillins. Warnings and precautions : · Tablets should not be crushed · Cefuroxime can affect the results of a test for blood sugar levels, or a blood screen called the Coombs test · Inform your doctor if you have a history of colitis, renal impairment, or seizure disorders Other medicines and Cefuroxime : Cefuroxime may interfere with · Antacids · Probenecid · Oral anticoagulants · Contraceptive pills How to take Cefuroxime : · Take Cefuroxime after food. This will help to make the treatment more effective. Swallow Cefuroxime tablets whole with some water. Don't chew, crush or split the tablets — this may make the treatment less effective. · The recommended dose : Adults The recommended dose of Cefuroxime is 250 mg to 500 mg twice daily depending on the severity and type of infection. Children The recommended dose of Cefuroxime is 10 mg/kg (to a maximum of 125 mg) to 15 mg/kg (to a maximum of 250 mg) twice daily depending on the severity and type of infection · Cefuroxime is not recommended for children aged under 3 months, as the safety and effectiveness are not known in this age group. · Depending on the illness or how you or your child responds to treatment, the initial dose may be changed or more than one course of treatment may be needed. Patients with kidney problems : If you have a kidney problem, your doctor may change your dose. Possible side effects : Stop using the product and seek immediate medical attention if you develop urticaria, rash, tightness of the chest, wheezing, hypotension How to store Cefuroxime : · Keep this medicine out of the sight and reach of children. · Store in the original pack at or below 30°C. · Do not use Cefuroxime if the tablets are chipped or there are other visible signs of deterioration.