Product Description: Vivazac belongs to a group of medicines knowns as angiotensin-II receptor antagonists. Angiotensin II is a substance produced in the body which binds to receptors in blood vessels causing them to tighten which results in an increased in blood pressure. Vivazac prevents the binding of angiotensin II to these receptors, causing the blood vessels to relax and the blood pressure to lower. Vivazac slows the decrease of kidney function in patients with high blood pressure and type II diabetes. Therapeutic Indications: Vivazac is used in adult patients to: Treat high blood pressure ( essential hypertension ) Protect the kidney in patients with high blood pressure, type 2 diabetes and laboratory evidence of impaired kidney function. How to use: Always take VIVAZAC exactly as your doctor has told you. Method of administration: Vivazac is for oral use. Swallow the tablets with a sufficient amount of fluid (e.g one glass of water ). You can take Vivazac with or without food. Try to take your daily dose at about the same time each day. It is important that you continue to take Vivazac until your doctor tells you otherwise. Patient with high blood pressure: the usual dose is 150 mg once a day. the dose may later be increased to 300 mg once daily depending on blood pressure response. Patient with high blood pressure and type 2 diabetes with kidney disease: in patients with high blood pressure and type 2 diabetes, 300 mg ( two tablets a day ) once daily is the preferred maintenance dose for the treatment of associated kidney disease. the doctor may advice a lower dose, especially when starting treatment in certain patients such as those on hemodialysis, or those over the age of 75 years. The maximal blood pressure lowering effect should be reached 4-6 weeks after beginning treatment. Use in children and adolescents: Vivazac should not be given to children under 18 years of age. if a child swallows some tablets, contact your doctor immediately. Caution & Warnings: Like all medicines, Vivazac tablets can cause side effects, although not everybody gets them. The following side effects have been reported: As with similar medicine, rare cases of allergic skin reactions ( rash, Urticaria), as well as localized swelling of the face, lips and/or tongue have been reported in patients taking irbesartan. if you get any of these symptoms or get short of breath, stop taking Vivazac and contact your doctor immediately. The frequency of the side effects listed below is defined using the following convention: Very common: at least 1 in 10 patients or more. if you suffer from high blood pressure and type 2 diabetes with kidney disease, blood tests may show an increased level of potassium. Common: at least 1 in 100 and less than 1 in 10 patients. Dizziness, feeling sick vomiting, fatigue and blood tests may show raised level of an enzyme that measures the muscle and heart function (creatine kinase enzyme ). In patients with high blood pressure and type 2 diabetes with kidney disease, dizziness when getting up from a lying or sitting position, low blood pressure when getting up from lying or sitting position, pain in joints or muscles and decreased levels of a protein in the red blood cells (hemoglobin) were also reported. Uncommon: at least 1 in 1000 and less than 1 in 100 patients. Heart rate increased, flushing, cough, diarrhea, indigestion heartburn, sexual dysfunction ( problems with sexual performance , chest pain. Ingredients: The active substance is : Irbesartan