Theophylline 60 mg/5 ml Syrup
What is Theophylline used for:
Theophylline is a bronchodilator (dilates and opens the bronchi airways), pulmonary vasodilator and smooth muscle relaxant.
It works by relaxing the smooth muscles of your bronchial airways and the blood vessels of your lungs.
This medicine is used for the treatment of the symptoms and reversible airflow blockage that is linked with multiple respiratory problems like chronic asthma (respiratory condition that causes difficulty breathing and wheezing) and other chronic lung diseases (e.g. chronic bronchi inflammation and emphysema which is a condition that causes damage to your air sacs).
Do not use Theophylline:
If you are allergic to Theophylline, or any of the ingredients in this medicine.
Tell your doctor about the allergy and what signs you had.
In children who are taking ephedrine (available in some cough medicines and decongestants).
Warnings and Precautions:
Stop the medication right away and talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath, skin rash, swelling of the face or neck, decreased blood pressure and dizziness.
Talk to your doctor if your symptoms are getting worse or are not improving after a few days of starting this medicine.
Talk to your doctor before starting this medicine if you have severe heart problems (including congestive heart failure and myocardial injury), hypertension (high blood pressure), hyperthyroidism (overactive thyroid glands), liver problems and epilepsy (convulsions).
Talk to your doctor before starting this medicine if you have peptic ulcer (sore in your stomach or bowel).
Talk to your doctor before starting this medicine if you are sensitive to Xanthine derivatives.
Smoking may increase theophylline removal from your body and therefore your doctor may recommend a higher dose if needed.
Talk to your doctor before starting this medicine if you are taking the herbal remedy St. John’s wort. This medicine should not be taken at the same time with St. John’s wort. Talk to your doctor if you already take this herbal product and ask for advice before you stop taking it.
Talk to your doctor before starting this medicine if you are taking beta-2 agonists (used to open the airways), corticosteroids (used to decrease inflammation), or diuretics (increase urination). Your doctor may recommend monitoring your potassium levels (especially if you have severe asthma) if needed since this medicine may potentiate the hypokalemic effect (decrease in potassium levels) of these medicines.
Do not repeat the same prescription without consulting your doctor first.
Your doctor may recommend some blood tests to verify the accuracy of the dose that you are taking.
Possible side effects:
Possible side effects include allergic reactions, stomach upset, palpitations, headache, difficulty sleeping, irritability or anxiety, feeling sick and nausea, restlessness, excitability, vomiting, diarrhea and muscle twitching.
Other medicines and Theophylline:
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medications including prescription medicines, over the counter medicines, herbals, vitamins and supplements.
If you are taking Cimetidine (stomach acid reducer).
If you are taking Allopurinol (used to treat gout).
If you are taking corticosteroids (used to decrease inflammation).
If you are taking Furosemide (diuretic).
If you are taking Isoprenaline (used to treat low heart rate).
If you are taking oral contraceptives (birth control).
If you are taking Thiabendazole (used to treat worm infections in the bowel).
If you are taking Isoniazid, Rifampicin, Ciprofloxacin, Norfloxacin, Erythromycin (antibiotics) or other antibiotics.
If you are taking Calcium Channel Blockers (used for some heart problems e.g. Diltiazem and Verapamil).
If you are taking Nizatidine (used to treat ulcers).
If you are taking Fluconazole (used to treat fungal infections).
If you are taking Carbimazole (used to treat hyperthyroidism).
If you are taking Propafenone or Mexiletine (used to treat some types of abnormal heart rhythms).
If you are taking Oxpentifylline (used to improve blood flow).
If you are taking Disulfiram (used to treat alcoholism).
If you are taking Viloxazine (used to treat depression).
If you are taking antivirals like Ritonavir or Interferon Alfa.
If you will be receiving Influenza vaccine.
If you are taking antiepileptics like Phenytoin, lithium, Aminoglutethimide, Primidone, Carbamazepine and Barbiturates.
If you are taking Sulfinpyrazone (used to treat gout).
If you are taking Fluvoxamine (used to treat depression).
If you are taking other Xanthines medicines.
If you are taking St. John’s Wort (herbal product used to treat depression).
How to take Theophylline:
Premature infants newborn – 6 weeks
Your doctor will determine a dose of theophylline syrup based on body weight (usual dose is 4 mg/kg/day).
Children 6 weeks – 6 months old
Your doctor will determine a dose of theophylline syrup based on body weight (usual dose is 10 mg/kg/day).
Infants 6 months – 1 year old
Your doctor will determine a dose of theophylline syrup based on body weight (usual dose is 12 – 18 mg/kg/day).
Children 1 year – 9 years old
Your doctor will determine a dose of theophylline syrup based on body weight (usual dose is 20 – 24 mg/kg/day).
Children 9 years – 12 years old, adolescent daily cigarette smokers and otherwise healthy adult smokers (less than 50 years old)
Your doctor will determine a dose of theophylline syrup based on body weight (usual dose is 16 mg/kg/day).
Adolescents 12 - 16 years
Your doctor will determine a dose of theophylline syrup or sustained release tablets based on body weight (13 mg/kg/day).
Adults and elderly
Recommended dose is 1 sustained release tablet (300 mg) orally every 12 hours.
Your doctor may increase the dose after 1 week of starting the medicine to 1 sustained release tablet (300 mg) orally three times daily if your body weight is more than 70 kg.
The syrup dose of this medicine in non-smoking adults (including elderly) who are otherwise healthy is 10 mg/kg/day (maximum dose is 900 mg/day).
Patients with heart decompensation or lung and/or liver dysfunction
Recommended dose of the syrup is 5 mg/kg/day (maximum dose is 400 mg/day).
How To Use:
Take medication exactly as recommended by your doctor.
Talk to your doctor or pharmacist if you are not sure.
It is recommended that you take your medication after food.
How to store Theophylline:
Keep out of the reach of children and pets
Store medication below 25 °C
Do not use beyond the expiry date mentioned on the box
Keep medication in its original pack to protect it from moisture and light
Do not use damaged tablets
Do not dispose medication in the wastewater or household waste A valid prescription should be available upon delivery