Primolut-N 5 mg 30 Tablets

• to treat irregular, painful or heavy periods
• to treat endometriosis (where tissue from the lining of the womb is present in places where it is not normally found)
• to treat premenstrual syndrome (also known as premenstrual tension)
• to delay periods

Do not take Norethisterone:

• if you are allergic to norethisterone or any of the other ingredients of this medicine
• if you have ever had a problem with your blood circulation.
• if you have any symptoms of a blood clot
• if you have any condition which makes you more at risk of a blood clot
• if you have ever suffered migraine with visual disturbance
• if you have (or are recovering from) a liver disease
• if you have (or have ever had) liver tumors
• if you have diabetes with damaged blood vessels
• if you have any type of cancer
• if you have problems with genital bleeding for which the cause is not yet known
• if you have a condition called endometrial hyperplasia which has not been treated
• if you have hepatitis C
• if you have had any of the following conditions when you were pregnant: yellowing of the skin (idiopathic jaundice of pregnancy) or itching of the whole body (pruritus of pregnancy)

Talk to your doctor or pharmacist before taking Norethisterone:

• if you smoke
• if you have diabetes
• if you are overweight (BMI ≥ 30 kg/m2)
• if you have high blood pressure
• if you have heart problems
• if you have had a thrombosis/embolism
• if you suffer from migraine, asthma, or kidney problems
• if you suffer from epilepsy
• if you have an inflammation of your veins
• if you have varicose veins
• if anyone in your immediate family has had breast cancer
• if you have previously had a condition called chloasma
• if you have previously suffered from depression
• if you or someone in your close family has ever had high blood levels of cholesterol or triglycerides.
• if you have a disease of the liver or gall bladder
• if you have certain rare medical conditions such as systemic lupus erythematosus, sickle cell disease, Crohn’s disease or ulcerative colitis
• if you have hemolytic uremic syndrome
• if you have a condition that occurred for the first time or worsened during pregnancy or previous use of sex hormones
• if you have hereditary angioedema
• if you have an intolerance to some types of sugar

Other medicines and Norethisterone:

Tell your doctor if you are taking, have recently taken or might take any other medicines. These include medicines used for the treatment of:

• epilepsy
• tuberculosis
• HIV and Hepatitis C Virus infections
• fungal infections
• bacterial infections
• certain heart diseases, high blood pressure
• arthritis, arthrosis
• high blood pressure in the blood vessels in the lung
• breathing problems
• muscle pain and/or muscle cramps

How to take Norethisterone:

• Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
• The number of tablets that you need to take and the number of days per month when you need to take them will depend on why the doctor has prescribed Norethisterone. A common dosage would be 2-3 tablets each day. For some conditions Norethisterone has to be taken every day, but this is not always the case. Ask your doctor or pharmacist, if you are not sure about the number of tablets that you need to take, when they should be taken or how long you should take them for. Swallow the tablets whole with a drink of water.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. Stop taking Norethisterone and speak to your doctor immediately if you experience any of the following:

• • migraine for the first time
• unusually bad headaches, occurring more often than before
• sudden changes to your eyesight, hearing or speech
• sudden changes to your senses of smell, taste or touch
• symptoms of blood clot formation or symptoms of inflammation of the veins combined with the formation of blood clots (thrombophlebitis):
• unusual pains in your legs
• unusual swelling of your arms or legs
• sharp pains in your chest or sudden shortness of breath
• crushing pains or feelings of heaviness or tightness in your chest
• coughing for no apparent reason
• one side of your body suddenly becoming very weak or numb

How to store Norethisterone

• Keep this medicine out of the sight and reach of children.
• Store in the original carton.
• Do not use this medicine after the expiry date which is stated on both the outer carton and on each blister strip of tablets after EXP. The expiry date refers to the last day of that month.
• Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.