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Therapeutic Indications Of Oximal 15 Mg Tablets Short term symptomatic treatment of acute mild to moderate pain in adults Symptomatic treatment of pain and inflammation in osteoarthritis in adults Symptomatic treatment of pain and inflammation in rheumatoid arthritis in adults Method Of Administration Of Oximal 15 Mg Tablets Use the lowest effective dose for the shortest duration consistent with individual treatment goals for the individual patient. Osteoarthritis and Rheumatoid Arthritis: Starting dose: 7.5 mg once daily The dose may be increased to 15 mg once daily Juvenile Rheumatoid Arthritis (JRA): 0.125 mg/kg once daily up to a maximum of 7.5 mg. JRA dosing using the oral suspension should be individualized based on the weight of the child. Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions. If you take more than you should, talk to a doctor or go to the hospital straight away. If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose. Do not take a double dose (two doses at the same time) to make up for the forgotten dose. Undesirable Side Effects Of Oximal 15 Mg Tablets Most common (≥5% and greater than placebo) adverse events in adults are diarrhea, upper respiratory tract infections, dyspepsia, and influenza like symptoms Adverse events observed in pediatric studies were similar in nature to the adult clinical trial experience Warnings & Special Precautions While Taking Oximal 15 Mg Tablets Concomitant use of this drug and warfarin may result in an increased risk of bleeding complications Concomitant use of this drug and aspirin is not generally recommended because of the potential of increased adverse effects including increased GI bleeding Concomitant use with this drug increases lithium plasma levels Concomitant use with NSAIDs may reduce the antihypertensive effect of ACE-inhibitors Due to the presence of sorbitol in this drug oral suspension, there may be a risk of intestinal necrosis (possibly fatal) when the oral suspension is administered concomitantly with sodium polystyrene sulfonate Serious gastrointestinal (GI) adverse events can be fatal. The risk is greater in patients with a prior history of ulcer disease or GI bleeding, and in patients at higher risk for GI events, especially the elderly. Elevated liver enzymes, and rarely, severe hepatic reactions. Discontinue use immediately if abnormal liver enzymes persist or worsen. New onset or worsening of hypertension. Blood pressure should be monitored closely during the treatment. Fluid retention and edema. Should be used with caution in patients with fluid retention or heart failure. Renal papillary necrosis and another renal injury with long-term use. Use with caution in the elderly, those with impaired renal function, heart failure, liver dysfunction, and those taking diuretics, ACE-inhibitors, or angiotensin II antagonists. The use of this drug in patients with severe renal impairment is not recommended Serious skin adverse events such as exfoliative dermatitis, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN), can be fatal and can occur without warning. Discontinue this drug at the first appearance of rash or skin reactions Serious and potentially fatal cardiovascular (CV) thrombotic events, myocardial infarction, and stroke. Patients with known CV disease/risk factors may be at greater risk Storage Conditions Of Oximal 15 Mg Tablets Store below 25°c Don’t refrigerate Keep this medicine out of the sight and reach of children. Store in the original package to protect from moisture. Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.
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