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Hydrochlorothiazide & Amiloride hydrochloride 50 mg/5 mg tablets What Hydrochlorothiazide & Amiloride hydrochloride is and what it is used for Hydrochlorothiazide & Amiloride hydrochloride is used for: • heart failure • high blood pressure • fluid retention caused by a liver disease called ‘cirrhosis’ Do not take Hydrochlorothiazide & Amiloride hydrochloride tablets • If you are allergic to hydrochlorothiazide and amiloride hydrochloride or any of the other ingredients of this medicine • If you have diabetes (a high blood sugar level) • If you have been told by your doctor you have high levels of urea, creatinine, potassium or calcium in your blood • If you are allergic to a type of antibiotic called sulfonamides, such as sulfamethoxazole • If you are allergic to acetazolamide which is a diuretic used to remove fluid from the body and to treat high pressure in the eye (glaucoma), heart problems and sometimes fits or epilepsy • If you are allergic to any other ‘thiazide’ water tablet (diuretic) • If you are taking a potassium supplement or medicine containing potassium or you eat potassium-rich foods • If you suffer from kidney or liver disease Warnings and precautions Talk to your doctor or pharmacist before taking Hydrochlorothiazide & Amiloride hydrochloride if: • you have been told by your doctor you have high levels of uric acid, cholesterol or triglycerides (a type of cholesterol) in your blood • you are taking digitalis such as digoxin - used for heart failure and abnormal heart beat • you are being given fluids by a tube inserted into one of your veins • you have recently suffered from severe vomiting or diarrhoea • you have Systemic Lupus Erythematosus • you are elderly • you have gout • you have had skin cancer or if you develop an unexpected skin lesion during the treatment. Possible side effects Like all medicines, Hydrochlorothiazide & Amiloride hydrochloride can cause side effects, although not everybody gets them. The following side effects may happen with this medicine: Stop taking Hydrochlorothiazide & Amiloride hydrochloride and see a doctor straight away, if you notice any of the following serious side effects that may occur. You may need urgent medical treatment: • allergic reactions - the signs may include inflamed blood vessels, difficulties breathing or swallowing, collapse, redness, blisters, peeling skin, muscle pains, chills, a general feeling of being unwell, ulcers in your mouth, eyes or genitals • irregular heart beat of your heart that can lead to fainting and dizziness, palpitations • fast heart beat, chest pains (angina) • bleeding from your gut - signs may include blood in your faeces or a darker color of faeces • liver problems such as jaundice - signs may include yellowing of the skin and/or whites of the eyes Other medicines and Hydrochlorothiazide & Amiloride hydrochloride Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines, including medicines obtained without a prescription. This includes herbal medicines. It is important to tell your doctor or pharmacist if you take: • angiotensin converting enzyme inhibitors (ACE inhibitors) such as enalapril used to treat high blood pressure or heart problems • angiotensin II receptor antagonists such as losartan - used to treat high blood pressure or diabetics with kidney damage • other medicines for high blood pressure • medicines for diabetes such as insulin or chlorpropamide • lithium - used for depression • non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin or ibuprofen - used to reduce high temperature (fever), pain or for arthritis • barbiturates - used to help you sleep or to reduce anxiety • painkillers such as codeine, dihydrocodeine, dextropropoxyphene, diamorphine, morphine, pentazocine and pethidine • cholestyramine and colestipol - used to treat high cholesterol (hyperlipidaemia) • steroids - used to treat lots of different conditions such as rheumatism, arthritis, allergic conditions, skin problems, asthma or a type of blood disorder • ciclosporin - used for rheumatoid arthritis or to prevent rejection after a transplant • ‘non-depolarising’ muscle relaxants such as tubocurarine How to take Hydrochlorothiazide & Amiloride hydrochloride Taking this medicine Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. You should take this medicine by mouth. The amount you take each day will depend on your illness. The number of tablets to be taken will be on the label of your medicine. The recommended doses are: High blood pressure • The usual starting dose is half a tablet each day • Your doctor may change your dose to one tablet given each day • Your doctor may spread out the dose or give it as a single dose Heart failure • The usual starting dose is half a tablet each day • Your doctor may change your dose • You should not take more than two tablets in a day Fluid retention due to cirrhosis • The usual starting dose is one tablet each day • Your doctor may change your dose • You should not take more than two tablets in a day How to store Hydrochlorothiazide & Amiloride hydrochloride Keep this medicine out of the sight and reach of children. Do not use the medicine after the expiry date which is stated on the carton after ‘EXP’. The expiry date refers to the last day of that month. Store below 25°C. Protect from moisture. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment. A valid prescription should be available upon delivery
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