- Lactulose is a drug that belongs to a class of medications called laxatives.
- It is used to help relieve constipation by making the stools softer and easier to pass.
- It works by drawing water into the intestines.
- It is used in hepatic encephalopathy (a decline in brain function that occurs as a result of severe liver disease) by reducing blood ammonia.
- Constipation is generally a symptom in which the bowel movement is less than three times a week.
- Constipation is very common, however, some people suffer from chronic constipation which can interfere with their ability to carry out their daily tasks.
- Chronic constipation also causes people to strain to defecate.
How to use:
_ Dosage in stool softening and constipation:
- Adults and adolescents: The recommended starting dose is 15-45 mL (10-30 g) followed by a maintenance dose of 15-30 mL (10-20 g).
- Children (7-14 years): The recommended starting dose is 15 mL (10 g) followed by a maintenance dose of 10-15 mL (7-10 g).
- Children (1-6 years): The recommended starting and maintenance dose is 5-10 mL (3-7 g).
- Infants under 1 year: The recommended starting and maintenance dose is up to 5 mL (up to 3 g).
Dosage in hepatic encephalopathy (adult):
_ The recommended initial dose is 30-45 mL orally three to four times daily followed by a maintenance dose:
- Adjust the dose depending on your response until you start producing 2-3 stools per day.
- The dose may be taken as a single daily dose or it may be divided into two daily doses.
- You can use the measuring cup that comes with the bottle to measure your dose.
- It may take a few days for the medicine to start working. The maintenance dose is determined based on your response.
- You can take the medicine regardless of meals.
- Dosages may be changed in some cases
- Flatulence (it goes away after a few days).
- Belly pain.
Pregnancy and lactation:
- If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
- It is a safe laxative during pregnancy.
- Drink plenty of water.
- Eat plenty of fiber.
- It is recommended to move more.
- Eat foods that contain probiotics or take a probiotic supplement.
- Regularity in going to the bathroom.
Warnings and Precautions:
- Talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath, skin rash, swelling of the face or neck, low blood pressure, and dizziness.
- Diabetes (high blood glucose levels)
- If you suffer from lactose intolerance (the inability to digest the sugar lactose normally).
- Call your doctor if you do not feel relief within several days of using the medicine.
- You may need higher doses if you are taking this medicine to treat hepatic encephalopathy (a decrease in brain function that occurs as a result of severe liver disease). Therefore, blood glucose levels can rise as a result of the higher amount of sugar being absorbed into the blood.
- Be sure to tell your doctor if you have diabetes and liver problems in order to adjust the doses of your diabetes medications.
- Do not use the medication for longer than necessary to prevent dehydration.
- Avoid taking other laxatives at the same time to prevent excessive gastrointestinal side effects.
- Store at a temperature below 25°C.
- Do not cool the medicine in the refrigerator.
- Keep this medicine away from children.
- Store in the original box.
- Do not use this medicine after the expiry date which is stated on the carton.
- The expiration date refers to the last day of the month.