What Neomycin, Polymyxin B, Dexamethasone is used for: Neomycin, Polymyxin B, Dexamethasone is a combination of a steroid and two antibiotics. It is used for the short term treatment of inflammation of the eye, where administration of an antibiotic is also required to prevent an eye infection. Do not take Neomycin, Polymyxin B, Dexamethasone: If you have any type of infection of the eye that is not being treated including viral, fungal or untreated parasitic eye infections or Tuberculosis of the eye. Use of steroids may make infections worse. If you have a red eye that has not been seen by a doctor. If you are allergic to dexamethasone, neomycin, polymyxin B. Warnings & Precautions: Do not inject or swallow this medicine. Do not wear contact lenses while using it. Consult your doctor or pharmacist before using this medicine if you have a disorder causing a thinning of the eye tissues. Consult your doctor or pharmacist if your eye pain, redness, swelling, or irritation gets worse or persists. You may become more susceptible to eye infections with the use of this product. If you use it for a long period of time you may: Have increased pressure in your eye(s). You should have your eye pressure checked regularly while using it. This is especially important in children, as the risk of corticosteroid-induced increased pressure in the eye may be greater in children and may occur earlier than in adults. The risk of corticosteroid-induced increase intraocular pressure and/or cataract formation is increased in predisposed patients (e.g. diabetes). Develop cataract Become more susceptible to eye infections Talk to your doctor if you experience swelling and weight gain around the trunk and in the face as these are usually the first manifestations of a syndrome called Cushing's syndrome. Suppression of the adrenal gland function may develop after stopping a long-term or intensive treatment with this drug. These risks are especially important in children and patients treated with a drug called ritonavir or cobicistat. Contact your doctor if you experience blurred vision or other visual disturbances. Talk to your doctor before using this drug if you have diabetes or have a family history of diabetes. Possible Side Effects: Eye irritation Increased tear production Other medicines and Neomycin, Polymyxin B, Dexamethasone: Tell your doctor or pharmacist about all medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Tell your doctor if you are taking any of the following medicines: Topical NSAIDs. Simultaneous use of topical steroids and topical NSAIDs may increase healing problems in your eye. If you are using ritonavir or cobicistat, as this may increase the amount of dexamethasone in the blood. If you are diabetic and you are taking, having recently taken or might take medicines for treatment of diabetes such as insulin, metformin or sulfonylureas such as chlorpropamide, as this combination may decrease the blood glucose lowering effect of these medicines. How to take Neomycin, Polymyxin B, Dexamethasone: The usual dose is 1 or 2 drops into the space between your eyelid and eye 6 times daily, or more frequently if required. Wash your hands before you start. Shake the bottle well. Twist off the bottle cap. Hold the bottle pointing down, between your thumb and fingers. Tilt your head back. Pull down your lower eyelid with a finger, until there is a ‘pocket’ between the eyelid and your eye. The drop will go in here. Bring the bottle tip close to the eye. Do this in front of a mirror if it helps. Do not touch your eye or eyelid, surrounding areas or other surfaces with the dropper. It could infect the drops. Gently press on the base of the bottle to release one drop at a time. Keep the eyelid closed, while applying gently pressure to the corner of your eye by the nose. This helps to reduce the amount of medicine getting into the rest of the body. If you are using other eye drops, wait at least 5 minutes after putting in the drops before using the other eye drops. Eye ointments should be administered last. How to store Neomycin, Polymyxin B, Dexamethasone: Keep this medicine out of the sight and reach of children. Do not refrigerate or store above 25°C. Keep the bottle tightly closed. Keep away from direct sunlight. Do not use the drops after the expiry date (marked ‘Exp’) on the bottle and the carton. The expiry date refers to the last day of that month. Stop using the bottle 4 weeks after first opening, to prevent infections. Medicines should not be disposed of via waste water or household waste. Do not pass this medicine on to others.