What is Levofloxacin used for
Levofloxacin is an antibiotic that belongs to a class of medicines called “fluoroquinolones”. It is indicated in the treatment of adult patients with bacterial infections in the following body parts:
• Lungs and bronchi
• Urinary tract (bladder and kidneys)
• Skin and soft tissues
Do not take Levofloxacin
If you are allergic to Levofloxacin, other quinolones, or any of the ingredients in this medicine. Tell your doctor about the allergy and what signs you had.
Warnings and Precautions
• Talk to your doctor or pharmacist if you develop allergic reactions such as shortness of breath, skin rash, swelling of the face or neck, decreased blood pressure and dizziness.
• This medication may increase the risk of tendinitis (inflammation of the cords that attach muscle to bone). Contact your doctor in case of muscle or joint pain and stiffness. Make sure to tell your doctor if you are 60 years of age or older, are taking steroids, or have kidney, heart or lung transplants.
• This medication may cause blood problems such as thrombocytopenia (low platelet count, platelets are responsible for wound healing and stopping bleeding) and other blood problems. Make sure to monitor for bleeding, delayed wound healing, easy bruising, feeling tired or dizzy, fever and looking pale.
• This medication may cause liver problems. Contact your doctor immediately if you experience liver problem side effects such as pale skin, yellow eyes, white stools, dark urine, fatigue, swelling of abdomen.
• This medication may cause confusion, anxiety, convulsions, depression and difficulty sleeping after the first dose.
• Use of this medication may be linked to Clostridium Difficile diarrhea (a bacterial infection in the gut that causes diarrhea). Make sure to tell your doctor if you experience diarrhea.
• This medication may cause tingling and numbness in your peripheries. If this happens, make sure to tell your doctor in order to prevent irreversible damage to the nerves.
• Make sure to tell your doctor about other medications that you are taking to prevent QT prolongation (a heart problem that causes a type of irregular rhythm) from happening.
• Make sure to tell your doctor if you have low potassium levels in your blood, known QT prolongation or other heart problems.
Possible side effects of Levofloxacin
Possible side effects of Levofloxacin include: allergic reactions, liver problems, tendonitis (inflammation of the cords that attach muscle to bone), like muscle or joint pain and stiffness, confusion, lightheadedness, diarrhea, tingling and numbness in your peripheries, signs of QT prolongation (like, lightheadedness, heart palpitations, weakness and blurred vision), photosensitivity (skin reactions after skin exposure to sun or UV light), headache, nausea, insomnia (difficulty sleeping), constipation and dizziness.
Other medicines and Levofloxacin
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medications.
• If you are taking sucralfate or antacids containing aluminum or magnesium (used for heartburn).
• If you are taking warfarin (blood thinner).
• If you are taking antidiabetic medications (used to lower blood glucose levels).
• If you are taking didanosine (used to treat HIV).
• If you are taking iron supplements.
• If you are taking multivitamin preparations containing zinc.
How to take Levofloxacin
Nocosomial pneumonia (hospital acquired infection of the lungs):
750 mg (1 tablet of 750 mg) orally once daily for 7 – 14 days.
Community acquired pneumonia (community acquired infection of the lungs):
500 mg (1 tablet of 500 mg) or 750 mg (1 tablet of 750 mg) orally once daily for 7 – 14 days or 5 days respectively.
Acute bacterial sinusitis (infection of the sinuses):
750 mg (1 tablet of 750 mg) or 500 mg (1 tablet of 500 mg) orally once daily for 5 days or 10 – 14 days respectively.
Acute bacterial exacerbation of chronic bronchitis (infection of airways in the lungs):
500 mg (1 tablet of 500 mg) orally once daily for 7 days.
Complicated skin and skin structure infections:
750 mg (1 tablet of 750 mg) orally once daily for 7 – 14 days.
Uncomplicated skin and skin structure infection (mild skin and mucous membranes infections):
500 mg (1 tablet of 500 mg) orally once daily for 7 – 10 days.
Chronic bacterial prostatitis (long-term infection of the prostate):
500 mg (1 tablet of 500 mg) orally once daily for 28 days.
Complicated urinary tract infection or acute pyelonephritis (complicated bladder or kidneys infection):
750 mg (1 tablet of 750 mg) or 250 mg (1 tablet of 250 mg) orally once daily for 5 days or 10 days respectively.
Uncomplicated urinary tract infection (mild urinary tract infection that does not involve the kidneys):
250 mg (1 tablet of 250 mg) orally once daily for 3 days.
Post exposure of anthrax inhalation (serious type of infection caused by anthrax spores inhalation):
500 mg (1 tablet of 500 mg) orally once daily for 60 days.
Use is not recommended in children and is limited for post exposure of anthrax inhalation; recommended dose for this indication is: 8 mg/kg (max dose: 250 mg) orally twice daily for 60 days for children who are 6 months of age or older and who weigh less than 50 kg. For children who are 6 months of age or older and who weigh more than 50 kg: follow adults dosing for this indication. Do not use in children below 6 months of age.
• Take tablet with or without food.
• Take tablet with a full glass of water.
• Take oral solution 1 hour before or 2 hours after food.
• Take oral solution and tablet at least 2 hours before or after didanosine, antacids (containing aluminum or magnesium), sucralfate, iron supplements and multivitamin preparations containing zinc.
• Take at the same time every day.
• Do not take for more or less than prescribed by your doctor.
• Do not stop taking your medication prior to the end of prescribed duration even if you start feeling better.
• Drink a lot of fluids while taking this medication.
How to store Levofloxacin
• Store tablets and oral solution at 15 to 30°C
• Keep out of the reach of children and pets
• Do not use beyond the expiry date mentioned on the box
• Keep medication in its original pack to protect it from moisture and light
• Do not use damaged pills
• Do not dispose medication in the wastewater or household waste