Latuda 74 Mg 28 Tablets

t is an antipsychotic drug used to treat certain cases of schizophrenia and certain cases of depression. It belongs to a group of medicines known as atypical antipsychotics, second generation. Dosage: It is necessary to adhere to the dosage and method of use of the drug prescribed by the specialist doctor. Adult dosage • 40 mg orally once daily initially; not to exceed 160 mg/day • Initial dose titration is not required; shown to be effective in a dose range of 40-160 mg/day Pediatric dosage • Children younger than 13 years of age: Safety and efficacy not established • Children 13-17 years of age: • Starting dose: 40 mg orally once daily; initial dose titration is not required • Effective dosage range: 40-80 mg/day; not to exceed 80 mg/day Bipolar Depression Adult dosage Monotherapy • 20 mg orally once daily initially; may increase the dose if needed, not to exceed 120 mg/day • In monotherapy study, a higher dose range (80-120 mg/day) did not provide additional efficacy compared to the lower dose range (20-60 mg/day) • Adjunctive therapy • 20 mg orally once daily initially; may increase the dose if needed, not to exceed 120 mg/day Pediatric dosage • Indicated as monotherapy for major depressive episode associated with bipolar I disorder (bipolar depression) in adolescents between 10-17 years of age • 20 mg orally once a day; initial dose titration is not required • May increase dose after 1 week based on clinical response; not to exceed 80 mg once daily, the effective dose range is 20-80 mg/day Latuda should be taken with food so that the meal provides at least 350 calories. Common side effects of Lurasidone include: • drowsiness, • weight gain, • tremors, • muscle stiffness, • slow muscle movement, • feeling restlessness, • inability to sit still, • nausea, • vomiting, • runny nose, and • sleep problems (insomnia) Contraindications • Hypersensitivity • Coadministration with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir, voriconazole, mibefradil) • Coadministration with strong CYP3A4 inducers (e.g., rifampin, St. John’s wort, phenytoin, carbamazepine) • Special precautions for storage Store in the original package in order to protect from light.