Kombiglyze Xr 5 / 500 Mg 30 Tablets

Product Name Kombiglyze Xr 5/500, Extended Release, Reduce Blood Glucose Level & Prevent Diabetes Complications - 30 Tablets Scientific Name Saxagliptin 5 Mg + Metformin 500 Mg Tablets Category Of Kombiglyze Xr 5/500 Tablets Oral Anti-Diabetic Drugs Mechanism Of Action Of Saxagliptin & Metformin Saxagliptin is an inhibitor of DPP-4, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1). Incretins help the body produce more insulin only when it is needed and reduce the amount of glucose being produced by the liver when it is not needed. Metformin decreases blood glucose levels by decreasing hepatic glucose production (also called gluconeogenesis) Metformin decreases the intestinal absorption of glucose Metformin increases insulin sensitivity by increasing peripheral glucose uptake and utilization Therapeutic Indications Of Kombiglyze Xr 5/500 Tablets This medicine is used to treat a type of diabetes called “type 2 diabetes” Saxagliptin and metformin work together to control your blood sugar. They increase the levels of insulin after a meal. They also lower the amount of sugar made by your body. Along with diet and exercise, this helps lower your blood sugar. This medicine can be used alone or together with other antidiabetic medicines, including insulin. Method Of Administration Of Kombiglyze Xr 5/500 Tablets Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. If your doctor prescribes this medicine together with sulphonylurea or insulin, remember to take this other medicine as directed by your doctor to achieve the best results for your health. The amount of this medicine that you will take varies depending on your condition and the doses you currently take of metformin and/or individual tablets of saxagliptin and metformin. Your doctor will tell you exactly the dose of this medicine to take. The recommended dosing is one tablet twice a day. If you have reduced kidney function, your doctor may prescribe a lower dose. Take this medicine by mouth. Take with a meal to lower your chance of getting an upset stomach. Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions. If you take more than you should, talk to a doctor or go to the hospital straight away. If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose. Do not take a double dose (two doses at the same time) to make up for the forgotten dose. Undesirable Side Effects Of Kombiglyze Xr 5/500 Tablets Although the following side effects are not common in everyone, some patients may complain from: Headache Muscle pain (myalgia) Being sick or indigestion (dyspepsia) Infection of the structures that carry urine (urinary tract infection) Infection of the upper airways Inflamed nose or throat such as with a cold or sore throat Inflamed stomach (gastritis) or gut, sometimes caused by an infection (gastroenteritis) Infection of your sinuses, sometimes with a feeling of pain and fullness behind your cheeks and eyes (sinusitis) Flatulence Dizziness Tiredness (fatigue) Pregnancy & Breastfeeding Precautions While Taking Kombiglyze Xr 5/500 Tablets If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Your doctor will discuss the possible risks and benefits of using this medicine during pregnancy and breast-feeding Non-Pharmacological Treatments & Advice For Diabetic Patients All carbohydrate affects blood glucose levels so it’s important to know which foods contain carbohydrates. Choose the healthier foods that contain carbs and be aware of your portion sizes. Eat less salt. Eating lots of salt can increase your risk of high blood pressure, which in turn increases the risk of heart diseases and stroke. And when you have diabetes, you’re already more at risk of all of these conditions. Eat more fruit and vegetable. This can help you get the vitamins, minerals, and fiber your body needs every day to help keep you healthy. You can always try low or zero-calorie sweeteners (also known as artificial sweeteners) to help you cut down sugar for example Steviana Sweetener or Tropicana Slim Sweetener Don’t forget to keep moving. Being more physically active goes hand in hand with eating healthier. Remember to measure your blood glucose level continuously by using home monitor like Accu-Check, Instant, Blood Glucose Monitor Thiozac Capsules & Neurobion Tablets will help you to reduce neuropathy induced by diabetes If you experience symptoms of hypoglycemia such as weakness, dizziness, increased sweating, fast heart beating, vision disorders, or difficulty in concentration, it usually helps to eat or drink something containing sugar. Warnings & Special Precautions While Taking Kombiglyze Xr 5/500 Tablets Talk to your doctor or pharmacist before taking this medicine: If you have type 1 diabetes If you have or have had a disease of the pancreas If you are taking insulin or an antidiabetic medicine known as ‘sulphonyl urea’ If you have had allergic reactions to any other medicines that you take to control the amount of sugar in your blood If you have a problem or take a medicine that can lower your body’s defense against infections If you have ever had heart failure or you have other risk factors for developing heart failure such as problems with your kidneys Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medications including over-the-counter non-prescription medicines, prescription medicines, herbal supplements, vitamins, and supplements. Storage Conditions Of Kombiglyze Xr 5/500 Tablets Store below 25°c Don’t refrigerate Keep this medicine out of the sight and reach of children. Store in the original package to protect from moisture. Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.