Silymarin has both hepatoprotective and regenerative actions. The mechanism of action is a reduction of the FR formed by toxins that damage the cell membranes (LPO) and competitive inhibition through hepatocyte external cell membrane modification. used as a natural treatment for things including cirrhosis, jaundice, hepatitis, and gallbladder disorders. Adult dosage in terms of hepatoprotection is 420 mg/day of extract (standardized to 70-80% silymarin) three times a day for 6-8 weeks Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions. If you take more than you should, talk to a doctor or go to the hospital straight away. If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose. Do not take a double dose (two doses at the same time) to make up for the forgotten dose.