Isosorbide Dinitrate 20mg capsules What Isosorbide Dinitrate is used for: It is a vasodilator and used in long-term treatment and prophylaxis of disorders of the coronary circulation. Angina pectoris and rehabilitation therapy following myocardial infarction. Do not take Isosorbide Dinitrate if: Hypersensitivity to Isosorbide Dinitrate Acute circulatory failure (shock, vascular collapse) Very low blood pressure Haemorrhage or those who are volume depleted You are taking phosphodiesterase inhibitors (eg sildenafil, tadalafil, vardenafil) Warnings & Precautions: Use with caution in patients with closed-angle glaucoma (increased intra-ocular pressure). Alcohol should be avoided during treatment as reduction capacity may be reduced. There is a possibility of precipitating haemolysis (rupture of red blood cells) if you have G6PD deficiency. Possible Side Effects: Headache Flushing Low blood pressure Other medicines and Isosorbide Dinitrate: Its use phosphodiesterase inhibitors (eg sildenafil, tadalafil and vardenafil) can cause worse low blood pressure Orthostatic hypotension (low blood pressure upon movement) may occur with the combined use of calcium channel blockers (like amlodipine), anti-hypertensive agents, phenothiazines and tricyclic anti-depressants (amitriptyline, imipramine,doxeplin). Use of alcohol may produce severe hypotension and collapse. How to take Isosorbide Dinitrate: For adults above 18 years: the usual dose is one tablet twice daily. Do not exceed 240 mg daily Do not open or crush Swallowed whole with water Do not stop the medication if not indicated by your healthcare provider Do not use beyond the expiry date How to store Isosorbide Dinitrate: Keep this medicine out of the sight and reach of children. Store below 25 °C. ° A valid prescription should be available upon delivery