Glucovance 500/2.5 Mg 30 Tablets

Glibenclamide / Metformin HCl 2.5mg / 500 mg tablet What Glibenclamide / Metformin HCl is used for: The combination Glibenclamide / Metformin HCl is used to lower blood sugar levels in patients with diabetes mellitus type 2 (non-insulin dependent) along with a proper diet and exercising. Do not take Glibenclamide / Metformin HCl: If you’re allergic to Metformin, Glibenclamide, other sulfonylureas, sulfonamides or any other component of this medicine. If you have diabetes mellitus type 1 (insulin dependent) If you have liver problems. If you have severe kidney problems. If you have lactic acidosis or diabetic ketoacidosis (very high blood sugar levels and you experience nausea, vomiting, frequent urination, fatigue and muscle weakness). If you are dehydrated (lost too much water from your body due to long-lasting or severe diarrhea, or if you have vomited several times in a row). If you have a severe infection, such as an infection affecting your lung or your kidney. If you are treated for acute heart failure or have recently had a heart attack, have severe problems with your circulation or have breathing difficulties. If you are taking a medicine called Bosentan for high blood pressure. If you drink a lot of alcohol. Warnings and precautions: Talk to your doctor about all your medical conditions before taking this medicine including: If you are recovering from an injury, operation, infections with fever, or from other forms of stress. If you have liver or kidney problems. If you have any heart problems. If you have a deficiency in an enzyme called glucose-6-phosphate dehydrogenase (G6PD). The medicine must be stopped a period of time before a major surgery. Talk to your doctor. This medicine may cause a rare but serious side effect called lactic acidosis, particularly if your kidneys are not working properly. Symptoms include abdominal pain, vomiting, muscle cramps, severe fatigue, difficulty breathing, and reduced body temperature and heartbeat. This medicine may cause low blood sugar levels (hypoglycemia) especially if you miss a meal, exercise more or drink alcohol. Symptoms include: nausea, hunger, shaking, dizziness, confusion, sleepiness, restlessness, difficulty speaking and sweating. You may take a sugar cube or some sweet juice to help it. Possible side effects: Stop using this product and seek immediate medical help if you develop rash; hives; itching; red, swollen, blistered, or peeling skin; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Serious side effects: Allergic reactions Low blood sugar levels (hypoglycemia) Lactic acidosis Liver problems Other medicines and Glibenclamide / Metformin HCl: Tell your doctor about all the medicines you are taking. Glibenclamide / Metformin HCl interacts a lot of with the following medicines: Other medicines used to treat diabetes Medicines use for high blood pressure Medicines used to lower blood cholesterol Certain antibiotics Anti-fungals Medicines to treat pain and inflammation Medicines to treat mood disorders Bosentan Phenytoin Steroids Digoxin Anti-coagulants such as Warfarin Birth control pills Some medicines used for asthma and nasal congestion Certain anti-virals Some medicines used for cancer Contrast dyes used for xray How to take Glibenclamide / Metformin HCl: This medicine is intended for adults only. Take as indicated by your doctor. Take with meals. The usual starting dose is Glibenclamide 1.25 – 2.5 mg / Metformin 500 – 1000 mg. it is given once or twice daily. How to store Glibenclamide / Metformin HCl : Store at room temperature 68 to 77°F (20 to 25°C). Keep this medicine out of reach of children. Do not use this medicine after the expiry date stated on the package. The expiry date refers to the last day of that month. Do not throw away any medicines via wastewater or household waste. A valid prescription should be available upon delivery