Gleran 30 mg 30 Tablets

What are the uses of Geleran? Treatment of type 2 diabetes (diabetes not dependent on insulin): as a monotherapy in addition to diet and exercise. Or used with other diabetes medications such as sulfonylureas, metformin or insulin. What are the contraindications for using Gilliran ? Known hypersensitivity to this drug. heart failure What are the side effects of Geleran? Edema, upper respiratory infection, heart failure, dental problems, muscle pain, headache, fatigue What are the precautions for using Gelleran? Warning Pioglitazone can cause or worsen congestive heart failure in some patients. Dosage should be discontinued or reduced if symptoms of heart failure appear. It is not recommended to treat patients with symptoms of heart failure with this medicine. It is not used in cases of diabetic ketoacidosis. After initiating treatment or increasing the dose, patients should be carefully monitored for signs and symptoms of heart failure (including rapid and excessive weight gain, shortness of breath, and/or oedema). Monitor liver enzymes before starting treatment, and periodically thereafter. Serum glucose and hemoglobase A1c (Hgb A1C) should be measured periodically to monitor and control blood sugar and therapeutic response. Pregnancy: It is used in cases where the risk is greater than the benefit. Lactation: Unknown. Children: Safety and efficacy not established. Use with caution: patients with liver disease and elevated liver enzymes. Bone fractures, especially in females. Edema patients: it may cause fluid retention. What are the drug interactions of GLIRAN? Oral contraceptives: Potential reduction in contraceptive effectiveness. CYP2C8 enzyme inhibitors (eg, azole antifungals [e.g. ketoconazole] fluvoxamine, gemfibrozil, trimethoprim) Pioglitazone levels in plasma are elevated, and pharmacokinetic effects and adverse reactions are increased. Pioglitazone increases levels of: Amidron, amphetamine, fluoxetine, dextromborphan, mirtazepine, nefazodone, paclitaxel, paroxetine, repliglinin, rosiglitazone. CYP2C8 inducers (phenytoin, phenobarbital, rifampin) reduce the plasma concentrations of pioglitazone, and reduce efficacy. What are the dosage forms of GLIRAN? 30 mg tablet What are the storage conditions for Geleran? Store at room temperature in a tightly closed container. Protect from heat and do not freezr.