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Diacerein 50mg 30CAP

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In stock
SKU :
1019-EV019

Diacerein 50 mg 30 Hard Gelatin Capsules :treating conditions such as:Osteoarthritis-Osteomalacia -Osteoporosis

Overview of Diacerein


Diacerein is a slow-acting drug from the anthraquinone family, primarily used to treat osteoarthritis. It works by inhibiting the action of interleukin-1, a protein involved in inflammation and cartilage degradation. Diacerein prevents the production of cytokines such as interferon-1, stimulates the synthesis of collagen and glycosaminoglycans, and possesses both anti-inflammatory and cartilage-protective properties.

 

Uses of Diacerein


Diacerein capsules are prescribed for:

Managing arthritis affecting joints like the knee and hip.
Reducing cartilage degeneration and modulating bone cell activity.
Alleviating joint pain and swelling while improving joint movement.
Treating conditions such as:Osteoarthritis
Osteomalacia
Osteoporosis
 


Mechanism of Action


Diacerein:

Inhibits interleukin-1 activity to curb inflammation.
Prevents the development and secretion of inflammatory cytokines.
Promotes cartilage health by stimulating collagen and glycosaminoglycans formation.
 


Side Effects of Diacerein


Common side effects may include:

Skin-related: Rash, eczema, itching.
Gastrointestinal: Abdominal pain, diarrhea (acute or chronic), pigmentation of the rectal mucosa.
Liver-related: Elevated liver enzymes, liver disorders, jaundice.
Other: Dark-colored urine.
 


Contraindications


Diacerein should not be used without medical supervision in the following cases:

Hypersensitivity to its ingredients.
Patients over 65 years of age.
During pregnancy or breastfeeding.
Patients with liver disease or a history of liver disorders.
Children under 15 years of age.
Inflammatory bowel diseases, such as Crohn's disease or ulcerative colitis.
Undiagnosed abdominal pain.
 

Precautions for Use


Stop usage and consult a doctor if severe diarrhea occurs.
Seek medical advice if symptoms like itching or jaundice appear, as these may indicate liver problems.
Use with caution in:Patients with gastrointestinal diseases or kidney failure.
Elevated liver enzyme levels.
Elderly patients over 65 years old.
 


Drug Interactions


Inform your doctor or pharmacist about any medications, herbs, vitamins, or supplements you are taking. Diacerein may interact with:

Warfarin
Aceclofenac
Antacids (e.g., aluminum hydroxide) – separate by at least 2 hours.
Cardiac glycosides
Diuretics (e.g., chlorothiazide)
 


Dosage and Administration


Diacerein should be taken with food, during breakfast and dinner, without opening the capsules. Drink with a full glass of water.
 Dose: One capsule daily for a month, then twice daily

 


Dosage Forms


Diacerein is available as 50 mg capsules, packaged in boxes containing 3 strips of 10 capsules each.
 


Storage Instructions


Store at temperatures not exceeding 30°C.
Keep in a dry place, away from moisture and direct sunlight.
Keep out of reach of children.
Do not refrigerate or freeze.

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