What Duloxetine is used for: Duloxetine is used to treat: Depression Generalized anxiety disorder (chronic feeling of anxiety or nervousness) Diabetic neuropathic pain (stabbing pain caused by advanced diabetes) Do not take Duloxetine: If you’re allergic to the active substances or any other component of this medicine. If you have liver disease. If you have severe kidney disease. If you are taking or have taken within the last 14 days a monoamine oxidase inhibitor (MAOI). If y are taking Fluvoxamine, Ciprofloxacin or Enoxacin. Warnings and precautions: Talk to your doctor about all your medical conditions before taking this medicine including: If you are taking other medicines to treat depression. If you have kidney problems. If you have had seizures (fits). If you have other mental problems. If you have eye problems, such as certain kinds of glaucoma (increased pressure in the eye). If you have a history of bleeding disorders. If are currently being treated with another medicine which may cause liver damage. It may take 2-4 weeks for the medicine’s effects to show. This medicine may cause suicidal thoughts, especially in young patient. If you have thoughts of harming or killing yourself at any time, contact your doctor or go to a hospital straight away. Possible side effects: Stop using this product and seek immediate medical help if you develop rash; hives; itching; red, swollen, blistered, or peeling skin; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Serious side effects: Suicidal thoughts Serotonin syndrome Very common side effects: Headache Sleepiness Other medicines and Duloxetine Tell your doctor about all the medicines you are taking. Duloxteine interacts with a lot of medicines including: Other medicines used for mental health problems Fluvoxamine Ciprofloxacin Enoxacin Medicines that cause sleepiness Diuretics Blood thinners How to take Duloxetine : Take as indicated by your doctor. Depression and diabetic neuropathy: the usual dose is 60 mg once a day. Generalized anxiety: the usual starting doe is 30 mg once a day. It will be increased to 60 mg if needed. How to store Duloxetine : Store at room temperature 68 to 77°F (20 to 25°C). Keep this medicine out of reach of children. Do not use this medicine after the expiry date stated on the package. The expiry date refers to the last day of that month.