Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension is indicated for the treatment of the following infections in adults and children:
Acute bacterial sinusitis (adequately diagnosed)
Acute otitis media
Acute exacerbations of chronic bronchitis (adequately diagnosed)
Community acquired pneumonia
Skin and soft tissue infections in particular cellulitis, animal bites, severe dental abscess with spreading cellulitis.
Bone and joint infections, in particular osteomyelitis.
How to use:
For adults and children ? 40 kg, this formulation of Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension provides a total daily dose of 1750 mg amoxicillin/250 mg clavulanic acid with twice daily dosing and 2625 mg amoxicillin/375 mg clavulanic acid with three times daily dosing, when administered as recommended below.
For children < 40 kg, this formulation of Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension provides a maximum daily dose of 1000-2800 mg amoxicillin/143-400 mg clavulanic acid, when administered as recommended below.
If it is considered that a higher daily dose of amoxicillin is required, it is recommended that another preparation of Co-amoxiclav 400/57mg/5ml Powder for Oral Suspension is selected in order to avoid administration of unnecessarily high daily doses of clavulanic acid .
The duration of therapy should be determined by the response of the patient.
Some infections (e.g.osteomyelitis) require longer periods of treatment.
Treatment should not be extended beyond 14 days without review .
Caution & Warnings:
Before taking this product, tell your doctor or pharmacist if you are allergic to amoxicillin or clavulanic acid; or to penicillin or cephalosporin antibiotics; or if you have any other allergies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Talk to your pharmacist for more details.
Before using this medication, tell the doctor or pharmacist your medical history, especially of: liver disease (including liver problems caused by previous use of amoxicillin/clavulanic acid), kidney disease (such as requiring dialysis), a certain type of viral infection (infectious mononucleosis).
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
This product may cause live bacterial vaccines (such as typhoid vaccine) to not work as well.
Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
During pregnancy, this medication should be used only when clearly needed.
Discuss the risks and benefits with your doctor.
This medication passes into breast milk.
Consult your doctor before breast-feeding.
Stop using this medicine and call your doctor at once if you have a serious side effect such as:
diarrhea that is watery or has blood in it;
pale or yellowed skin, dark colored urine, fever, confusion or weakness;
easy bruising or bleeding;
skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
agitation, confusion, unusual thoughts or behavior, seizure (convulsions);
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
mild diarrhea, gas, stomach pain;
nausea or vomiting;
skin rash or itching;
white patches in your mouth or throat; or
vaginal yeast infection (itching or discharge).