What Nebivolol is used for: Nebivolol is a beta-adrenergic blocking agent indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. Do not take Nebivolol if you have: Hypersensitivity to Nebivolol Severe bradycardia Heart block greater than first degree Cardiogenic shock Decompensated cardiac failure Sick sinus syndrome (unless a permanent pacemaker is in place) Hepatic impairment Warnings & Precautions: Acute exacerbation of coronary artery disease upon cessation of therapy: Do not abruptly discontinue. Diabetes: Monitor glucose as β-blockers may mask symptoms of hypoglycemia. Possible Side Effects: Fatigue Headache Other medicines and Nebivolol: Tell your doctor or pharmacist about all medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your doctor if you are taking any of the following medicines: CYP2D6 enzyme inhibitors (fluoxetine, bupropion, paroxetine, amiodarone) may increase nebivolol levels. Reserpine or clonidine may produce an excessive reduction of sympathetic activity. Both digitalis glycosides (digoxin, digitoxin) and β-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can increase the risk of bradycardia. Verapamil- or diltiazem-type calcium channel blockers may cause excessive reductions in heart rate, blood pressure, and cardiac contractility. Antacids (e.g. cimetidine), are used to treat excessive stomach acid. If you are being treated for excessive stomach acid, you should take nebivolol during a meal, and the antacid drug between meals. Asthma medications, medications for the blocked nose (e.g. pseudoephedrine) or for certain eye disorders such as glaucoma (increased pressure in the eye) or dilation of the pupil. How to take Nebivolol: For hypertension: Adults above 18 years old: the recommended dose is 5mg once daily. For chronic heart failure: Adults above 18 years old: the recommended initial dose is 1.25mg daily. This may be increased after 1-2 weeks to half a tablet daily (2.5mg) and then to 1 tablet daily (5mg). This may be further increased to a maximum recommended dose of 2 tablets daily (10mg). You can take it with or without food. If you want to increase the dose for further reduction in blood pressure wait 2 weeks interval. If renal or hepatic impairment stating dose is 2.5mg. How to store Nebivolol: Keep this medicine out of the sight and reach of children. Store Nebivolol between 68° to 77°F (20° - 25°C). Safely throw away Nebivolol that is out of date or no longer needed.