ِAdazio 300mg 30 Tabs.

Product Name

Adazio, 300 Mg, Film-Coated - 30 Tablets

Scientific Name

Quetiapine 300 Mg Tablets

Category

Antipsychotic Drugs

Mechanism of Action

The exact mechanism of action of quetiapine is not fully understood, but several proposed mechanisms exist:

In schizophrenia, it may work by antagonizing dopamine type 2 (D2) and serotonin 2A (5HT2A) receptors.
In bipolar depression and major depressive disorder, its effects may be due to the binding of quetiapine or its metabolite to the norepinephrine transporter.
Additional effects, such as somnolence, orthostatic hypotension, and anticholinergic effects, may result from the antagonism of H1 receptors, adrenergic α1 receptors, and muscarinic M1 receptors, respectively.

Therapeutic Indications

Quetiapine is used to treat various conditions, including:

Bipolar depression and major depressive episodes in major depressive disorder: Symptoms may include sadness, guilt, lack of energy, loss of appetite, or difficulty sleeping.
Mania: Symptoms may include excitement, elation, agitation, enthusiasm, hyperactivity, poor judgment, aggression, or disruptiveness.
Schizophrenia: Symptoms may include hallucinations, delusions, suspiciousness, anxiety, confusion, guilt, tension, or depression.
Method of Administration
Take your tablets once a day.
Do not split, chew, or crush the tablets. Swallow them whole with water.
Take your tablets without food (at least one hour before a meal or at bedtime, as directed by your doctor).
Avoid grapefruit juice while taking Quetiapine as it can affect the medication's efficacy.
Continue taking your tablets even if you feel better, unless advised otherwise by your doctor.
Your doctor will determine your starting dose and maintenance dose based on your illness and needs.
Doses may be adjusted in special circumstances, so always follow your doctor's or pharmacist's instructions.
If you take more than the prescribed dose, seek medical attention immediately.
If you miss a dose, take it as soon as you remember unless it's nearly time for your next dose. Do not take a double dose to make up for the missed one.

Undesirable Side Effects

Side effects may vary, but some patients may experience:

Dizziness (which may lead to falls), headache, dry mouth.
Feeling sleepy (this may diminish over time with continued use).
Discontinuation symptoms such as insomnia, nausea, headache, diarrhea, vomiting, dizziness, and irritability.
Abnormal muscle movements, such as difficulty starting movements, shaking, restlessness, or muscle stiffness without pain.
Changes in levels of certain fats (triglycerides and total cholesterol).
Rapid heartbeat.
Constipation, indigestion.
Weakness.
Swelling of arms or legs.
Low blood pressure when standing.
Increased blood sugar levels.
Blurred vision.
Abnormal dreams and nightmares.
Irritability.
Disturbance in speech and language.
Shortness of breath.
Vomiting (mainly in the elderly).
Fever.
Changes in thyroid hormone levels.
Decreases in certain types of blood cells.
Increases in liver enzymes.
Elevated prolactin levels in the blood.

Pregnancy & Breastfeeding Precautions

If you are pregnant, breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor or pharmacist before using this medicine.
Your doctor will discuss the potential risks and benefits of using this medicine during pregnancy and breastfeeding.