A valid prescription needed upon order collection Ketorolac tromethamine 0.45% ophthalmic solution What Ketorolac tromethamine is used for: Ketorolac tromethamine is a nonsteroidal anti-inflammatory drug. The ophthalmic solution is indicated for the treatment of pain and inflammation following cataract surgery. Do not take Ketorolac tromethamine if: Beyond 24 weeks of amenorrhea (5 months of age pregnancy) Hypersensitivity to Ketorolac tromethamine History of asthma triggered by the use of Ketorolac tromethamine or substances of similar activity such as other NSAIDs, aspirin Gastrointestinal haemorrhage, cerebrovascular haemorrhage or another evolving haemorrhage An evolving gastric ulcer or intestinal Severe hepatic impairment Severe renal impairment Severe uncontrolled heart failure. Warnings & Precautions: Delayed Healing: Topical nonsteroidal anti-inflammatory drugs (NSAIDs) may slow or delay healing. Tell your doctor if you are taking topical corticosteroids There is the potential for cross-sensitivity to acetylsalicylic acid, phenylacetic acid derivatives, and other NSAIDs. There have been reports of bronchospasm or exacerbation of asthma associated with the use of ketorolac tromethamine ophthalmic solution in patients who either have a known hypersensitivity to aspirin/non-steroidal anti-inflammatory drugs, or a past medical history of asthma. Increased Bleeding Time: With some NSAIDs, there exists the potential for increased bleeding time due to interference with thrombocyte aggregation. It is recommended that ophthalmic solution be used with caution in patients with known bleeding tendencies or who are receiving other medications, which may prolong bleeding time. If you have evidence of corneal epithelial breakdown should immediately discontinue use of topical NSAIDs and should be closely monitored for corneal health. If you used more than 1 day prior to surgery or used beyond 14 days post-surgery may increase risk for the occurrence and severity of corneal adverse events. It should not be administered while wearing contact lenses. Possible Side Effects: High pressure in the eye Headache Blurred vision Other medicines and Ketorolac tromethamine: Tell your doctor or pharmacist about all medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Tell your doctor if you are taking any of the following medicines: Topical corticosteroids are also known to slow or delay healing. Concomitant use of topical NSAIDs and topical steroids may increase the potential for healing problems. Several substances are involved in interactions, due to their antiplatelet medicinal products properties: aspirin and NSAIDs, ticlopidine and clopidogrel, tiro¬ban, epti¬batide and abciximab, iloprost. The use of several antiplatelet agents increases the risk of bleeding. How to take Ketorolac tromethamine: Adults: One drop should be applied to the affected eye twice daily beginning 1 day prior to cataract surgery, continued on the day of surgery, and through the first 2 weeks of the postoperative period. If administered in conjunction with other topical ophthalmic medications such as alpha-agonists, beta-blockers, carbonic anhydrase inhibitors, cycloplegics, and mydriatics. Drops should be administered at least 5 minutes apart. How to store Ketorolac tromethamine: Keep this medicine out of the sight and reach of children. Store at 15°-30°C (59°-86°F). Store the vials in the pouch, protected from light. Fold pouch ends closed.